| Formula Ingredients |
Benefits of Each |
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Vitamin B6
Pyridoxal 5' Phosphate (PLP)
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- It is a cofactor in more than 150 enzymatic reactions associated with blood sugar regulation, immunity, cardiovascular function, neuronal health, and metabolic and digestive health.
- Reduces plasma glucose (blood sugar levels) by inhibiting the activity of small-intestinal α-glucosidases (enzymes associated with glucose metabolism).
- Functions as an antioxidant by counteracting the formation of reactive oxygen species (inflammatory markers) and advanced glycation end-products.
- May support blood sugar regulation in women with gestational diabetes.
- Cofactor for enzymes involved in DNA metabolism.
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| Niacin (Vitamin B3) |
- Vitamin B3 supports cardiovascular health by inhibiting hepatic(liver) triglyceride synthesis, reducing very low-density lipoprotein (VLDL) secretion, and increasing HDL plasma concentrations.
- Reduces conversion of VLDL into LDL proteins and serum lipoprotein concentrations in plasma (blood).
- Vital for regulation of gene expression, cell cycle progression, DNA repair, and cell death.
- It supports a healthy inflammatory response via antioxidant and anti-apoptotic (preventing cell death) properties.
- Prevents pathologies(diseases) such as Pellagra and reduces the prevalence of nervous anorexia, cancer, and Crohn's disease.
- It supports tumor sensitization to radiation via the tumor mass's apoptosis (cell death) cascade and improves oxygen delivery to malignant tissues (cancer cells).
- Supports cognitive health by reducing the age-related decline of NAD+, increasing quinolinic acid, and reducing neuroinflammation.
- Increased niacin-associated NAD+ levels have increased neurotransmission, learning, and memory.
- Niacin reduces the prevalence of neurodegenerative pathologies by preventing mitochondrial dysfunction.
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Caffeine Anhydrous
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- Optimizes energy, cognitive function, and mental alertness.
- Supplementation with caffeine has been shown to enhance acute exercise performance.
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| L-Citrulline Malate |
- Supports cardiovascular health and exercise performance by increasing l-arginine production.
- It increases nitric oxide production, improves exercise performance, and increases blood flow when exercising skeletal muscle.
- Supports strength increases, exercise endurance, and recovery.
- May reduce blood pressure by increasing vascular function.
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| Bioperine |
- Increases absorption of amino acids and curcumin.
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| Folate (Folic Acid) |
- May support proper cell growth and DNA synthesis.
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| Vitamin B-12 (Methylcobalamin) |
- A metabolically active, methylated form of Vitamin B12 is needed for proper DNA synthesis, folate cycle function, energy production, cognitive function, and immune health.
- Aids as an antioxidant via direct scavenging of reactive oxygen species (inflammation), preserving l-glutathione levels (master antioxidant), and reducing oxidative stress.
- May prevent vitamin B12 deficiency diseases such as anemia, neurodegenerative disease, cardiovascular disease, and osteoporosis.
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| Creatine Monohydrate |
- Optimizes exercise performance, muscle mass, strength, thermoregulation, recovery, and intramuscular stores of phosphocreatine (PCr).
- Vital for the energy reaction of every cell in the human body as a spatial energy shuttle and energy sensor.
- Vital in brain bioenergetics (metabolic activity).
- Fuels CD8 and CD4 T- cell-mediated immunity (immune cells) in cancer tissue.
- It supports cognition and focus by replenishing cerebral creatine storage (creatine in the brain).
- Supports cognitive health in brain creatine deficiency-associated neurodegenerative diseases.
- Supports cognitive health by facilitating synaptic glutamate and neurotransmitter uptake.
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| N-Acetyl Tyrosine |
- Supports memory, cognitive flexibility, brain executive function, and convergent thinking.
- A precursor to dopamine is vital for dopamine synthesis in the brain.
- Supports cognitive function in individuals with high amounts of stress and anxiety.
- Increases dopamine levels in highly stressed individuals.
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| Choline Bitrate |
- Essential for cell membrane integrity, cell messaging, fat metabolism, DNA synthesis, immune support, and nervous system function.
- Serves as a methyl donor and precursor for cell membrane production.
- Precursor for acetylcholine (neurotransmitter), which activates receptors in the central nervous system, mediated immune responses (α7nAchR).
- Lifelong choline supplementation may combat neurodegenerative diseases by reducing amyloid-β plaque load (plaques of degrading neurons).
- Reduces the total homocysteine concentration (inflammation marker) in individuals with low folate levels and other B vitamins (B₂, B₆, and B₁₂).
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| DMAE Bitrate |
- Increases acetylcholine levels in the brain.
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| L-Theanine |
- A unique non-protein amino acid found in green tea (Camellia sinensis).
- Supports mood, mental clarity, cognitive health, and memory, and is a natural antidepressant/neuroprotective agent.
- Aids as an antidepressant due to partial antagonism for the N-methyl-D-aspartate receptor, manifesting its cognitive optimizing effects.
- Reduces the neuropsychiatric side effects of chronic adolescent THC exposure.
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| Bacopa Monnieri |
- It supports cognitive function, memory, and alertness, and is an anti-stress agent.
- May combat inflammatory conditions such as asthma, bronchitis, dropsy, and rheumatism.
- Bacopa has been shown to have anti-inflammatory effects on macrophages (immune cells) and inhibits the release of IL-6 and TNF-α (inflammatory markers) from monocytes (immune cells).
- A promising candidate for the development of novel therapeutics that target neuroinflammation and have the potential for treating a wide range of CNS disorders, including Alzheimer's disease, depression, and schizophrenia.
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